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Swisher SG , Holmes EC, Hunt KK, Zinner MJ, McFadden DW

In recent years, the global prevalence of T2DM has increased exponentially, and its disease burden is closely related with obesity, sedentary lifestyle and genetic susceptibility (Sun et al., 2022)

10.17305/bjbms.2020.4711 Bosn J Basic Med Sci

Thus, these reports not only reveal a novel ferroptosis surveillance system, the CoQ/FSP-1 system but also solve the long-existing mystery as to why CoQ (CoenzymeQ, ubiquinone), an essential component of the mitochondrial electron transfer chain (ETC), is also located in extramitochondrial spaces where CoQ function was not known (Morr and Morr, 2011)