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However, contrary to earlier reports suggesting an association with HFE gene polymorphisms, later clinical studies demonstrated that allele frequencies in Wilson disease patients are comparable to those in the general population [100]

glycoproteins and proteoglycans are responsible for epithelial-ECM and epithelial-mesenchymal crosstalk, cell proliferation, adhesion, migration, differentiation and survival

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Retinoid side effects include dryness, peeling, redness, and increased sun sensitivity that many users find intolerable