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In contrast, a high level of p-Drp1 (Ser637) in NPC patients is associated with a longer DFS and OS, suggesting that either serine 616 or serine 637 phosphorylation of Drp1 is a prognostic biomarker of NPC patients

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To overcome these challenges, engineered nano-drug delivery systems that facilitate efficient BBB penetration and pathology-responsive release are crucial for the clinical applicability of lactylation-targeted therapies