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In endothelial cells, elevated indoxyl levels cause oxidative stress, a pro-inflammatory response, and increased adhesion molecule expression

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Integrating findings across these different models may allow us to build a more holistic picture of SCZ pathophysiology, facilitating the exploration of new research avenues and informed decision-making for interventions

Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats