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These include prodrug strategies, nanotechnology-based delivery systems, conjugation with different polymers (e.g., PEG), encapsulation with the use of metalorganic frameworks, targeted delivery using ligand conjugation (e.g., peptides and antibodies), or manufacture of inhalable devices (e.g., intranasal administration)

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intravenously injected frozen-thawed or fresh mitochondria into mice resuscitated from cardiac arrest, it was found that injection of fresh mitochondria elevated ATP content and increased survival from 55% to 91% at 72 h after resuscitation from cardiac arrest

& Liu, P