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Additional evidence of the metabolic consequences of proteasome inhibitors is also provided by their interaction with mTOR, an integrator of environmental signals to regulate protein synthesis, autophagy, cell proliferation, growth and survival that plays a key role in MM and other cancers (55, 56)

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Int J Environ Res Public Health 20(5):3948 Rammali S, Hilali L, Dari K, Bencharki B, Rahim A, Timinouni M, Khattabi A (2022) Antimicrobial and antioxidant activities of Streptomyces species from soils of three different cold sites in the Fez-Meknes region Morocco