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[1] [2] The clinical trials that supported FDA approval did not identify muscle cramps or leg cramps as occurring at a significantly higher rate in semaglutide-treated patients compared to placebo groups

Oncogene 37 , 32163228 (2018)

Vanani, H

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The most common preparation error is injecting air into the vial during reconstitution, which creates pressure differentials that pull contaminants through the needle on subsequent draws