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median age 84) enrolled at 5 centers, had low pre-stroke morbidity (median mRS: 0)

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The RT-PCR analysis showed that expression levels of ZFTF gene in the ZFTF-3 strain under the MT-free condition were even up to 3.8-fold of the WT strain under the MT-treatment condition, indicating that the Padh4 is a strong promoter to efficiently drive the ZFTF gene expression with stronger induction effect under MT treatment

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