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And we may be asymptomatic while all this is happening, but this will not prevent B12 from remaining low, methionine synthase from malfunctioning, and homocysteine from accumulating

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No trial reported on clinical signs and symptoms of vitamin B 12 deficiency, health-related quality of life, or acceptability of the treatment scheme Orally taken vitamin B 12 showed lower treatment-associated costs than intramuscular vitamin B 12 in one trial

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The board discussed that measuring serum B12 concentrations to monitor B12 treatment should be decided on a case-by-case basis (for example, when people show new symptoms, to check compliance with oral treatment, and to check whether B12 was absorbed after oral administration)