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Ketogenic Diet for ASD The ketogenic diet is a general term for a low-carbohydrate, moderate-protein, and high-fat diet that encourages our body to use ketones instead of glucose for energy

Guo, R., Guo, X., Li, T., Fu, X., & Liu, R

Activated caspase-4/5/11 specifically cleaves GSDMD to release the N-terminal pore domain (NT), leading to cell membrane perforation and pyroptosis (105)

Overall, while semaglutide and tirzepatide remain effective options, mazdutide may offer enhanced metabolic benefits through its combination of appetite suppression, energy expenditure, and targeted fat loss, making it a promising candidate for patients with obesity complicated by metabolic disorders

To further support that ER knockdown induced ferroptosis, ER+ breast cancer cells were exposed to the ferroptosis inhibitor Ferrostatin-1