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Description

Biomed Pharmacother 177:116996

Matsunaga N, Ogino T, Hara Y, Tanaka T, Koyanagi S, Ohdo S

Nussenzweig, S

after 3 months of treatment, notable improvement was noted on right side in the form of decreased shades of pigmentary network (in cases of epidermal melasma) and decreased irregularity of pigmentary network, decreased number of granules and globules (in cases of mixed melasma)

Histological analysis confirmed that miR-ADSCs enhanced eNOS and VEGFa expression in penile tissues, reduced apoptosis, and preserved smooth muscle integrity, suggesting that miR-423-5p inhibition in ADSCs enhances their therapeutic efficacy for DMED by simultaneously upregulating the eNOS and VEGFa pathways [102]