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Indeed, defects in TfR recycling were established to be a common anomaly in fibroblasts from different subtypes of NBIA patients [150, 151], suggesting impaired iron incorporation as a shared mechanism responsible for iron overload in these pathologies

doi: 10.1038/s41467-022-34064-4 81 FuQXuLWangYJiangQLiuZZhangJet al

Clinical Manifestations: Patient may report shortness of breath and cough

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[38] [39] DNP's risks were highlighted in the Chamber of Horrors , an exhibit assembled by the United States Food and Drug Administration (FDA) to explain the limitations of existing American drug regulations