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Consider intramuscular vitamin B 12 injections instead of oral replacement for suspected or confirmed vitamin B 12 deficiency caused by diet if: The person has another condition that may deteriorate rapidly and have a major effect on their quality of life (for example, a neurological or hematological condition such as ataxia or anemia)

The authors of one trial (95) included in the above-mentioned meta-analysis (89) noted that little cognitive decline was observed in the placebo group over their two-year trial, which may have limited their power to detect an effect of the B-vitamin intervention (95)

Typically, 1 ampoule 2-3 times weekly for therapeutic use, or once weekly/monthly for maintenance, administered intramuscularly or intravenously

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These combined effects create an optimal cellular environment for fat metabolism, energy production, and metabolic health