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The complex interplay between immune suppression and activation, elevated peripheral pro-inflammatory cytokines and other inflammatory markers, and cytokine involvement in neurophysiology suggests that inflammation is a key pathological mechanism underlying depression (7376)

Mechanick, Jeffrey I

W Aoi, Y Ogaya, M Takami, et al

Oncolytics 17 , 518530 (2020)

In addition, a subset of autistic people have strong biochemical evidence of mitochondrial dysregulation, especially of mitochondrial bioenergetics, although the percentages vary widely across studies depending on the autistic population studied and the biomarkers used (50)