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17 Extremely rare mutations in the TCN2 gene may result in severe intracellular cobalamin depletion

In summary, the fact that NNMT plays a role in a number of diseases/conditions makes development of NNMT inhibitors an important path to developing therapeutics to treat various diseases/conditions

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however, they arent made to handle rapidly flowing water and an overflow is still possible if the volume is greater than what the drain can handle

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