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This is especially important considering that mitochondria are the primary sites of ATP and ROS production and are critically involved in balancing pro- and anti-apoptotic signals [1, 4]

Villegas, R., Martin, S.M., O?Donnell, K.C., Carillo, S.A., Sagasti, A., and Allende, M.L., "Dynamics of degeneration and regeneration in developing zebrafish peripheral axons reveals a requirement for extrinsic cell types", Neural Development 7 (1): (2012)

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78 A subsequent single-cell sequencing study demonstrated that these immunosuppressive neutrophils exhibit high PD-L1 expression and attenuate the innate immune response by promoting an increased proportion of Tregs