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In addition, CL-bromelain was reported for its suppression of ERK, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase (145)

The ethanolic extract of BM at the dose of 200 mg/kg showed a good hepatoprotective effect in nitrobenzene-induced liver damage in mice model by an increase in SOD, CAT and GPx enzymes and by normalizing the serum marker enzymes such as aspartate transaminase, alanine transaminase, and alkaline phosphatase