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That separation is the main reason this combination is pharmacologically rational

While there is no treatment or way to prevent the metallic taste due to chemotherapy drugs, certain measures can help, such as avoiding metal utensils, which can increase the sensation of a metallic taste, and serving food cold or at room temperature to slightly mask the taste of food

The efficacy of this therapeutic combination was first validated in our breast cancer models, demonstrating that PHGDH wild type breast cancer cells do not respond to the therapeutic combination, whereas PHGDH-amplified breast cancer cells exhibited a synergistic sensitivity to suboptimal dosages of sertraline plus chloroquine (Figure S8A)

At home, she shares her space with a beloved Siamese cat, whos always by her side

Appropriate sterile techniques must be followed, e.g., cleaning the injection site with an alcohol wipe thoroughly prior to the injection