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Mirzoyan K, Klavins K, Koal T, Gillet M, Marsal D, Denis C, et al

However, prolonged exposure to FFAs hampers glucose-induced insulin secretion and insulin production, potentially resulting in apoptosis-mediated -cell death

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Immunohistochemistry and immunofluorescence techniques confirmed the upregulation of 4HNE, which is a specific end product of ferroptosis, further confirming its involvement in kidney injury, as previously demonstrated (Ide et al., 2021

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