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ROS upregulate the expression of Nucleolin, n-Myc, Ddx17, and Syne2, which are most widely known for their positive participation in steps throughout ribosome biogenesis, including synthesis and processing of rRNAs, assembly of ribosomal proteins, transport to the cytoplasm and association of ribosomal subunits 29,30,43,44

[DOI] [PubMed] [Google Scholar] 7.Rubin DT, Huo D, Kinnucan JA, Sedrak MS, McCullom NE, Bunnag AP, et al

A yellow oval in Panel B indicates that the enzyme is affected by estradiol and/or testosterone, and therefore, its activity is different in females than males