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Description

Cattaneo, 1999

Elbatreek MH, Pachado MP, Cuadrado A, Jandeleit-Dahm K, Schmidt H

Pharmacokinetics Blood-Brain Barrier Neuro-oncology Mechanistic Studies of Redox Regulation and Oxidative Stress Investigators can utilize BSO hydrochloride to create a precisely controlled, pharmacologically induced GSH deficiency

Add freshly made (this is critical) 0.1 M NaOH to the Dynabeads-DNA complex and incubate at room temperature for 2-3 min (maximum 5 min) with rotation

Notably, while previous studies have largely used peripheral tissues like serum and plasma, our study used whole-brain tissue to measure redox biomarkers