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All family members from both families were then screened for confirmation for the presence of the identified mutation in the MLH1 gene by Sanger sequencing using standard protocols on an ABI 3730xl instrument using the following oligomers purchased from PxLence (Ghent, Belgium) (Cat #: PXL A0182967

Fifteen trials have investigated combinations of Phyllanthus and antiviral drugs (INF-, lamivudine, adefovir dipivoxil, thymosin, vidarabine), and demonstrated significant improvements associated with combination therapy over antiviral drugs alone, such as reducing blood levels of HBV DNA & HBV antigen, and increasing immune response to HBV (Xia 2011)

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These differing rates may be in result of variable treatment protocols, different methods of diagnosing recurrence, and inconsistent follow-up