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Filtering of the Disease-Causing Variants Primary filtering out of low-quality reads and probable artifacts and the subsequent annotation of variants were performed using standard methods

Expression of Grin1, Grin2a, Grin2b and Grin2d receptor-subunit genes was also assessed in the hippocampus

Moreover, clinical studies suggested that estradiol treatment was able to revert endothelial dysfunction in post-menopausal women with atherosclerotic, non-stenotic arteries by preventing acetylcholine-induced coronary vasospasm (114)