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First, ferroptosis can lead to the death of leukocyte subsets and the corresponding loss of immune function

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Considering the principle of how NK cells participate in eliminating M.tb infected cells is not clear, further investigations are needed to understand the role of antibody-mediated NK cell activation in protecting against M.tb infection and TB development

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found that hyperglycemia increases the expression of cleaved Bax and Caspase-3 in human microvascular endothelial cells (HMEC-1), promoting apoptosis, oxidative stress and inflammation