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Description

Compared to a similarly unoptimized ENL PROTAC designed with a traditional CRBN ligand, dHTC1 afforded several other improvements, including improved selectivity, more durable degradation over time, and better pharmacokinetic properties

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The origins of genomic duplications in Arabidopsis

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Data processing Tumor size was measured as the sum of manually contoured tumor areas in each slice multiplied by slice thickness using in-house software 49

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Typically improves within 2-4 weeks at each dose level

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