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Antioxid Redox Signal 4(3):405414 Urata Y, Yamamoto H, Goto S, Tsushima H, Akazawa S, Yamashita S, Nagataki S, Kondo T (1996) Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells

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Economic Challenges and Lack of Incentives for Pharmaceutical Companies From an economic point of view, there is very little investment in antibiotic research and development (R&D) from the pharmaceutical industry to allow the development of new antibacterials [59]

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