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Given that 70% of Mel and 85% of insulin-stimulated glucose disposal enters the skeletal muscle, the enhancement of insulin sensitivity and glucose balance by MOTS-c may be mediated in this tissue

Ketogenic diet elicits antitumor properties through inducing oxidative stress, inhibiting MMP-9 expression, and rebalancing M1/M2 Tumor-associated macrophage phenotype in a mouse model of colon cancer