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Notably, the SAC-treated group was positioned between the control and model groups, deviating from the model group towards the control group along the PC1 direction, suggesting that SAC intervention partially reversed the metabolic disorders induced by the model condition

The combination of UK-5099 with JMF4073 depleted dTTP and dCTP pools to achieve both in vitro and in vivo therapeutic effects

320 Although all cystines located on the surface of p53 can be modified by the Michael addition reaction, cystine 124 is considered the most important site