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El NOEL para el comportamiento reproductivo de las ratas macho en un estudio de alimentacin fue de 50 mg/kg al da tras una exposicin de 90 das

Conflicting results were reported in further studies with large patient numbers, which failed to demonstrate an antioxidant or oxidant balance [74, 103]

Pharmacol Res Perspect 6(2):e00388 Leoung GS, Stanford JF, Giordano MF, Stein A, Torres RA, Giffen CA, Wesley M, Sarracco T, Cooper EC, Dratter V et al (2001) Trimethoprim-sulfamethoxazole (TMP-SMZ) dose escalation versus direct rechallenge for Pneumocystis Carinii pneumonia prophylaxis in human immunodeficiency virus-infected patients with previous adverse reaction to TMP-SMZ

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