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Novel applications: Beyond conventional fertility treatments While antioxidants have traditionally been used as dietary supplements to improve natural sperm quality by mitigating oxidative damage, emerging research has revealed their potential for novel applications that extend well beyond conventional fertility therapies

Another important unanswered question concerns the pathophysiological interactions between astrocytes and other glial cells, such as microglia and oligodendrocytes, under neurodegenerative conditions and their associated microenvironments

Limited information is available regarding use in patients with kidney disease

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MiR-155 inhibits the negative regulators of the TLR4 pathway, thereby reducing their expression, promoting macrophage sensitivity to lipopolysaccharide (LPS), and increasing the production of pro-inflammatory TNF in the liver, thus aggravating the inflammatory response [39]