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Intact accumulating -catenin is allowed to translocate from the cytoplasm into the nucleus for the activation of oncoprotein promoter DNAs

Neuropsychopharmacology 27:470478

However, recent research has highlighted the potential to repurpose existing drugs to target AD pathology

The TLR7 agonist Imiquimod alleviates DSS-induced colitis in mice by inducing the expression of type I interferons (IFN) and antimicrobial peptides (AMPs) and inhibits the survival of intracellular pathogens such as Salmonella [31]