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10.1172/jci65566 J

Dranoff, J

PubMed Jastreboff, A.M., Aronne, L.J., Ahmad, N.N., Wharton, S., Connery, L., Alves, B., et al

the capacity of HGF to induce new synaptic connections and stimulate neurogenesis in the hippocampus supports the use of HGF mimetics for the treatment of depression

The work supports the broader HGF/c-Met mechanism beyond the hippocampal cognitive context, and the zebrafish protection model has been further studied in subsequent work in mammalian systems