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First, SELECT was not a primary prevention trial, and the data should not be extrapolated to all individuals with overweight and obesity to prevent major adverse CV events

By labs and clinical assessment, not a preset formula

Choline and inositol with methionine work together to metabolize fat and keep it from building up in the liver

Similarly, Cu + directly binds to lipoylated dihydrolipoyl transacetylase (DLAT), inducing lipoylated DLAT aggregation and ultimately leading to cuproptosis

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