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Surprisingly, L-DKO mice did not die or significantly lose weight shortly after genetic deletion was induced (Fig

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median age (months) 60 (20,142) vs 13 (8, 43), p 0.3

2011 Jan;409(1):46-53

Moreover, a recent study demonstrated that ALDH2 could alleviate MIAinduced oxidative stress, inflammation and apoptosis in chondrocytes via inhibiting aquaporin 4 expression [88]