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Appendix 1 describes the literature search strategy

Due to the complexity, and size limitations associated with the cobalamins, the primary method for calculating ground state properties is density functional theory (DFT), while time-dependent DFT (TD-DFT) is used for electronically excited states

Nervous System and Mood Support B6, B9, and B12 contribute to the production of neurotransmitters such as serotonin and dopamine, improving focus, reducing anxiety, and stabilizing mood

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