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Furthermore, owing to their ability to act as free radicals, prevent lipid peroxidation, activate antioxidant enzymes, regulate immune responses, and exhibit prebiotic properties that influence the composition of the gut microbiota, flavonoids demonstrate antioxidant and anti-inflammatory properties (Urban et al

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unlike that of MDM2, the E3 ubiquitin ligase activity of MDM4 is deficient

Therefore, the present review provides a comprehensive overview of potential therapeutic targets provided by ferroptosis-related pathways in stroke, providing new insights into how ferroptosis can be exploited to treat stroke

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