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AD is characterized by the accumulation of amyloid-beta (A) plaques and neurofibrillary tangles composed of hyperphosphorylated tau protein [152]

therefore, it must be transported into the cells by SLC7A11 (xCT) in exchange for glutamate, which implies that SLC7A11-mediated GSH biosynthesis largely relies on glutamine metabolism 55

The liver has multiple functions, including the ability to metabolize drugs via CYP450 enzymes

Overcoming the compensatory increase in NRF2 induced by NPL4 inhibition enhances disulfiram/copper-induced oxidative stress and ferroptosis in renal cell carcinoma

Each new generation adds either additional receptor targets or combination strategies that push weight loss outcomes further