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Indeed, there was a 44-fold increase in bacterial burdens in LysM - Atg5 -/- BMDMs as compared to WT BMDMs or control Atg5 fl/fl BMDMs upon BSO treatment (Fig

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Therefore, in COVID-19, the imbalance in the cellular redox state with an excess of free radicals (ROS) and activation of inflammatory signaling pathways cause tissue damage [27]

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Because dietary intake of calcium and vitamins K and D is often inadequate, including for patients on a gluten-free diet, routine supplementation with vitamin K at the time of diagnosis of celiac disease has been suggested (Mager 2012)

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