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However, when bleeding finally does occur, it's often heavier because the uterine lining has built up unchecked due to unopposed estrogen, she explains

Ethics declarations Ethics approval and consent to participate The study protocol was approved by the ethics committee of Guilan University of Medical Sciences (IR.GUMS.REC.1400.197) in accordance with the World Medical Associations code of ethics (Declaration of Helsinki, revised in Brazil 2013), and registered at an ICMJE and WHO recognized registry of clinical trials (www.irct.ir) at 28/08/2021 (registration number: IRCT20200920048782N1)

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A deficiency in B12 can lead to fatigue, memory problems, and weakness