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However, IBN mice exhibited markedly impaired oligodendrocyte regeneration and remyelination compared to control mice in the presence of interferon (IFN-) ( + mice developed much more severe EAE because oligodendrocytes from these mice were more vulnerable to inflammation than those from control mice ( Oligo ) showed a decrease in the loss of mature oligodendrocytes, which in turn prevented demyelination upon EAE challenge ( Oligo mice was more dependent on controlling oligodendrocytes themselves, while the change in inflammation was not significant

Chew EY, Clemons TE, Sangiovanni JP, Danis RP, Ferris FL III, Elman MJ, et al

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Clin Chim Acta 325(12):165170

As with any medication, potential side effects, drug interactions, and contraindications should be reviewed with a healthcare provider