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On the other hand, UVB-induced tyrosine nitration in melanocytes stimulates main photosensitizers, including methylene blue and pheomelanin, to reversely enhance ROS generation 99

Therefore, this section focuses on the pathological damage, molecular mechanisms, and prognostic impact of Cu dysregulation in DM and its complications ( Table 2 ) ( Figure 2 )

Lesku and Schmidt, 2022)

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Advancements in genetic techniques have led to substantial progress in developing conventional lines with improved oxidative stress tolerance or by developing transgenic lines with modified antioxidant levels