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Description

Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism

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This finding raises the possibility of an important role of antioxidant function in modulating lifespan

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[DOI] [PubMed] [Google Scholar] 137.Kikuchi A., Ohashi K., Sugie Y., Sugimoto H., Omura H

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The AMPK signaling pathway plays a core role in the regulation of energy metabolism, lipid metabolism, inflammation, and autophagy and has become an important target for the prevention and treatment of NAFLD

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It contains a -glutamyl bond between glutamate and cysteine, which is critical for its activity

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