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They achieve this by transforming harmful ROS into less reactive or non-toxic by-products

Lu C-X, An X-X, Yu Y, Jiao L-R, Canarutto D, Li G-F, et al

The SASP secreted by senescent chondrocytes increases matrix metalloproteinase (MMP) activity, leading to the breakdown of cartilage and the progression of osteoarthritis.28 Cancer: While cellular senescence serves as a protective mechanism against tumorigenesis by halting the proliferation of damaged or oncogene-expressing cells, the chronic inflammatory environment created by senescent cells can promote cancer progression