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Interestingly, the PKC pathway can also be activated by FSHR via formation of IP3 and DAG and this leads to the expansion of cumulus cells and meiotic maturation of oocytes (123), again neatly demonstrating crosstalk between gonadotropin GPCRs and GH/IGF signaling., The interconnection of these signaling systems at least partly explains the physiological effects observed in vitro / ex vivo

To confirm the mechanism of hyperoxia liquid on oxidative stress in CPB induced rat model, Nrf2-ARE signaling pathway was analyzed using Western blot

H.HuaP.HeC.YuH.ShaoD.et al (2022)

Bullous and Exfoliative Skin Toxicity: Permanently discontinue for severe and life-threatening bullous, blistering or exfoliating skin toxicity

Trends Microbiol 29 , 606620 (2021)