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A multi-year open-label observational study in elderly patients reported improvements in self-reported sleep quality and physical performance scores, although study designs lacked blinding and modern placebo control

Sgouras et al

However, in agreement with a causal role of moderately elevated circulating homocysteine levels in cardiovascular disease, some putative mechanisms have been identified that may explain the atherothrombogenicity of hyperhomo- cysteinemia

Mice in all the experiments were at least 9 weeks old at the starting point of various diets unless described specifically

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