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However, concentrations up to 80 M Erastin or 10 M RSL3 induced less than 50% cell death (Fig

Individual ingredients of Protandim are well-known antioxidants that cause induction of SOD and catalase in rodents and diminish cellular lipid peroxidation (Joe, Vijaykumar, & Lokesh, 2004

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OCR was measured following sequential injections of 2.5 M oligomycin A, 2.5 M BAM15, and 0.5 M rotenone/antimycin A (all Agilent, Seahorse XF T Cell Metabolic Profiling Kit, 103772-100) according to the manufacturers instructions

(14) Specifically, the phenolic ring structures are responsible for ROS scavenging