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Accordingly, glutamine metabolism plays a role in gene expression through the contribution of -ketoglutarate and succinate to chromatin structure modification

Advances in mass spectrometry and chemical probe design have facilitated the development of more sensitive redox proteomics methods, such as the NEM-biotin switch assay or the Gsp-biotin assay to study targets for protein S -glutathionylation at a global scale (Lind et al., 2002