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There is some evidence that hormone therapy may help some women with osteoarthritis

The most commonly reported side effects were mild and included headache, minor gastrointestinal disturbances (flatulence, mild diarrhea at high doses), upper respiratory symptoms, and mild injection site reactions

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The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )

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