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doi: 10.1007/s00438-016-1250-8 80 KangJSongYZhangZWangSLuYLiuX

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There are many topoisomerases, and James Wang, one of the discoverers of these enzymes, has described them further

Single-voxel 1 H MR spectra were acquired from a volume of interest (VOI = 20 20 25 mm 3 ) in the medial prefrontal cortex using a short-TE spin-echo full-intensity acquired localized single voxel spectroscopy technique (SPECIAL) with the following scan parameters: TE/TR = 6/4000 ms, acquisition bandwidth = 2 kHz, number of averages = 148, vector size = 2048

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