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THP-1 macrophages were chosen due to their critical role in the intestinal immune response, where they act as key regulators of inflammation

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Basal levels of ROS, RNS, and RSS are physiologically generated in cells and serve important regulatory and mediator functions

Once-daily morning administration produces superior outcomes compared to split protocols

It can be said that it is more beneficial in terms of neuroprotection, especially in the short-term and male groups